The rapid onset of action for a drug that reduces agitation in patients with schizophrenia or bipolar disorder is a key component for adequately managing these disorders. Strategies for improving the treatment of agitation, along with disease symptoms, may help to alleviate the suffering-as well as the economic impact-of these disorders. 7,8 The tendency for agitation to lead to violent behavior is compounded if substance abuse is involved. 5Īgitation, which is defined as excessive motor and verbal activity, is frequently observed in psychiatric patients and affects the treatment of schizophrenia and bipolar disorder. 1,5,6 In addition, the hospital admission rate for patients with bipolar disorder is 29% versus <5% for patients with depression. ![]() 1,4 Bipolar disorder is considered the most expensive behavioral health diagnosis, costing more than twice as much as depression per affected individual. The lifetime prevalence of bipolar disorder is 2.4% worldwide and 4.4% in the United States this disorder is more common among women than among men. ![]() 1 According to a recent study, the indirect costs attributed to schizophrenia between 20 totaled approximately $75 billion. For example, schizophrenia often results in unemployment and is considered a major cause of long-term disability worldwide. ![]() More than 5% of individuals in the United States are diagnosed with schizophrenia or bipolar disorder 1,2 these conditions can have a significant impact on health economics and personal productivity.
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